Yes the injectors could be toast, but before even considering that, there are other things to look at. Knowing the year model of yours is important - at least it lets us know if you have a DPF. Look on your dash as you turn on the key - if there's a light like you see in the below photo in the bottom centre, you have (or had) a DPF fitted to the vehicle and that could be the cause.
The DPF needs to "regenerate" and when doing so, uses some extra fuel. If it's doing it all the time, you could be using quite a bit of juice. If your DPF has been removed (look under the front passenger floor, the DPF is a larger tube that mounts inline in the exhaust and has several little pipes coming out of it. If yours is missing and you have the light, maybe your DPF sensors are shot - you should talk to auggie (a user on this forum) about some new sensors.
If you don't have the light, other things that can cause extra fuel consumption are:
1) Dragging brakes. Drive the car for 5 minutes and feel the hub/wheel nut temps. They should all be the same temp and not overly hot.
2) CAS misalignment. If the car starts well and idles smoothly the CAS is probably fine, but if it's a little hesitant the timing needs to be checked.
3) Faulty/failed turbocharger actuator. Some of the ST models had electronic actuators that needed to be replaced by Nissan. If it's vacuum-operated, it could be vac hoses (very common), vac solenoid (common), brake booster (uncommon, accompanied by poor braking performance), actuator diaphragm (uncommon), vac pump (very uncommon).
4) Faulty fuel rail pressure sensor. Possibly it's been interfered with by a performance chip, which often modify the return signal to fool the ECU into raising the fuel rail pressure.
Questions:
a) Is there any smoke evident, at various times, and what colour is it?
b) Does the car perform well? Dragging off Hiluxes at the lights can be done in Park with the engine off, handbrake on and a chain tying you to a nearby pole so that's no real test, try dragging off a performance vehicle like a Hyundai Getz. Can you do it?
c) Does your car have a performance chip? Try disabling it. There may be a control for it in the cabin (DP Chip, Steinbauer, ChipIt, Unichip, No Limits - there are many to choose from, some infinitely better than others).