If you are talking about a break where the bleeder outlet is, I used the workaround detailed here and it worked fine. One slight difference though is I installed a brass elbow I bought from (I think) Tradelink rather than have a long length of hose looping around and prone to a kink. Much tidier too.
I did this a couple of years ago and have had no trouble since.
Sans bleeder you just need to be careful filling/topping up coolant to make sure there is no air trapped in system. I typically park it on an incline or some ramps so the radiator is the highest point then fill slowly.